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Singapore Clinical Trial: AFFIRM: A Randomized, Double-Blind, Placebo-Controlled, Study to Evaluate the Effect of Seladelpar on Clinical Outcomes in Patients with Primary Biliary Cholangitis (PBC) and Compensated Cirrhosis

Singapore, July 15 -- The Health Sciences Authority received information related to the study titled 'AFFIRM: A Randomized, Double-Blind, Placebo-Controlled, Study to Evaluate the Effect of Seladelpar... Read More


Singapore Clinical Trial: A Single-arm Phase 2 Multicenter Study of Evorpacept in Combination with Trastuzumab and Chemotherapy in Participants with Metastatic HER2-Positive Breast Cancer

Singapore, July 15 -- The Health Sciences Authority received information related to the study titled 'A Single-arm Phase 2 Multicenter Study of Evorpacept in Combination with Trastuzumab and Chemother... Read More


Singapore Clinical Trial: An Operationally Seamless Phase 2/3 Study to Evaluate the Safety, Efficacy,and Pharmacokinetics of Enlicitide Decanoate in Pediatric Participants with Heterozygous Familial Hypercholesterolemia

Singapore, July 15 -- The Health Sciences Authority received information related to the study titled 'An Operationally Seamless Phase 2/3 Study to Evaluate the Safety, Efficacy,and Pharmacokinetics of... Read More


Singapore Clinical Trial: A Phase 3, Randomized, Open-label Study of Belzutifan + Zanzalintinib Versus Cabozantinib in Participants with Advanced RCC who Experienced Disease Recurrence During or After Prior Adjuvant Anti-PD-1/L1 Therapy (LITESPARK-033)

Singapore, July 15 -- The Health Sciences Authority received information related to the study titled 'A Phase 3, Randomized, Open-label Study of Belzutifan + Zanzalintinib Versus Cabozantinib in Parti... Read More


Singapore Clinical Trial: A double-blind, randomized, placebo controlled pilot trial to assess the efficacy of L. reuteri in patients with Functional dyspepsia

Singapore, July 15 -- The Health Sciences Authority received information related to the study titled 'A double-blind, randomized, placebo controlled pilot trial to assess the efficacy of L. reuteri in... Read More


Singapore Clinical Trial: A Phase 1, Randomized, Placebo-Controlled, Single and Multiple Ascending Dose-Escalation Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of LY4064912 in Healthy Participants and Participants with Overweight or Obesity.

Singapore, July 15 -- The Health Sciences Authority received information related to the study titled 'A Phase 1, Randomized, Placebo-Controlled, Single and Multiple Ascending Dose-Escalation Study to ... Read More


Singapore Clinical Trial: Topical Therapy for Closure of Small to Medium-Sized Macular Hole

Singapore, July 15 -- The Health Sciences Authority received information related to the study titled 'Topical Therapy for Closure of Small to Medium-Sized Macular Hole'. The following are the other re... Read More


Singapore Clinical Trial: A multicentre, randomised, double-blind, parallel group, placebo-controlled trial to assess the effects of oral TRPC6 inhibitor BI 764198 taken over a 104 week treatment period in adult and adolescent participants with primary focal segmental glomerulosclerosis (pFSGS) or genetic FSGS related to TRPC6 gene variants

Singapore, July 15 -- The Health Sciences Authority received information related to the study titled 'A multicentre, randomised, double-blind, parallel group, placebo-controlled trial to assess the ef... Read More


Clinical Trial: Radiofrequency in Knee Osteoarthritis

U.S., July 15 -- ClinicalTrials.gov registry received information related to the study (NCT07700784) titled 'Radiofrequency in Knee Osteoarthritis' on July 08. Brief Summary: Knee osteoarthritis is o... Read More


Singapore Clinical Trial: A multicentre, randomised, double-blind, parallel group, placebo-controlled trial to assess the effects of oral TRPC6 inhibitor BI 764198 taken over a 104 week treatment period in adult and adolescent participants with primary focal segmental glomerulosclerosis (pFSGS) or genetic FSGS related to TRPC6 gene variants

Singapore, July 15 -- The Health Sciences Authority received information related to the study titled 'A multicentre, randomised, double-blind, parallel group, placebo-controlled trial to assess the ef... Read More